Common Questions Asked When Starting Transdermal Hormones

Many of us need even more hormones than the Standard of Care provides. Starting physiologic restoration to achieve the blood levels normally found in young, healthy, cycling females is key.

Using compounded hormone creams to mimic ovarian estradiol and corpus luteum progesterone in amounts designed to produce a 28 day cycle produces results that are self evident.

What are the optimum blood ranges for physiologic restoration?

Optimum ranges include: Day 12 estradiol - 350 to 550 pg/ml Day 12 progesterone will be 0.3-0.5 ng/dl . Day 21 progesterone 10 -22 ng/dl. Day 21 estrogen should be 150-250 pg/ml . .Note: These ranges are for a healthy, young 20-25 year old. It is best to use the same lab so you are measuring with the same measurement.

Do I have to test blood every month?

No, it takes a few months for the receptors to come on board so you may wait until the third month to test and then examine the results with your doctor who may change your hormone doses. It is important to look at symptoms too. If you don't feel well and are showing symptoms of being low on a hormone check with your doctor. Thereafter many women only test periodically. It's good to test when you feel good to know what that looks like and also when you feel bad. Stress can bring the levels down very fast. The important thing is you don’t want to be hovering in the area below the blood ranges if you have symptoms.

Why do we need to get blood levels on days 12 and 21?

By testing on days 12 and 21 we can assure ourselves that we are reproducing a normal cycle of a younger woman. Day 12 is better to see the estrogen peak. Check both estradiol and progesterone on both days. Day 21 is the progesterone peak but check both progesterone and estradiol. Try to do this about one to two hours after applying your cream. Don't put cream on the area where the needle will enter. Checking on both days 12 and 21 will show an inverse relationship between the hormones.

Why do we need to get blood tests?

Blood tests are done to get a baseline so your doctor can adjust for accuracy. You will also make sure that you are getting into the ranges of healthy young women of 50 years ago who had low levels of diseases of aging. It can be very hard to learn about your symptoms without the help of blood testing.

Why Physiologic Restoration?

Physiologic Restoration only makes sense. You are restoring hormones to normal levels of young healthy females. Why would you want to restore any other way?